Synthesis of Polyfunctionalized Pyrroles by a PPh3-Promoted Condensation Reaction Between Ammonium Acetate, Dialkyl Acetylenedicarboxylate and Arylglyoxals
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Abstract:
A simple and efficient synthesis of some polyfunctionalized pyrrole derivatives by a triphenylphosphine-promoted condensation reaction between dialkyl acetylenedicarboxylates, arylglyoxals, and ammonium acetate is described. This present method carries several advantages, such as good yields, a simple procedure, non-hazardous reaction conditions and starting from easily accessible substrates
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Journal title
volume 36 issue 5
pages 17- 22
publication date 2017-10-01
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